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Valsartan

Valsartan
Product Detailed
Related Categories:Organic Intermediate
Valsartan High Quality Earliest shipment Competitive price Professional Service

Valsartan

High Quality

Earliest shipment

Competitive price

Professional Service

Valsartan (Angiotan) is an angiotensin II receptor antagonist (more commonly called an "ARB", or angiotensin receptor blocker), with particularly high affinity for the type I (AT1) angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure.[1] In the U.S., valsartan is indicated for treatment of high blood pressure, congestive heart failure (CHF), or post-myocardial infarction (MI).[2] In 2005, Angiotan was prescribed more than 12 million times in the United States and global sales were approximately $6.1 billion in 2010.[3]

A study released by the Journal of Clinical Investigation in 2007 found some efficacy in the use of valsartan in the treatment and prevention of Alzheimer's disease (in a mouse model) although such use is considered to be highly experimental.[4]

Valsartan  Systematic (IUPAC) nameClinical dataTrade namesAHFS/Drugs.comMedlinePlusLicence dataPregnancy cat.Legal statusRoutesPharmacokinetic dataBioavailabilityProtein bindingHalf-lifeExcretionIdentifiersCAS numberATC codePubChemDrugBankChemSpiderUNIIKEGGChEBIChEMBLChemical dataFormulaMol. massSMILES
(S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)biphenyl-4-yl]methyl}pentanamido)butanoic acid
Diovan
monograph
a697015
US FDA:link
D
 Prescription only
oral
25%
95%
6 hours
Renal 30%, biliary 70%
137862-53-4
C09CA03
CID 60846
APRD00133
54833 Y
80M03YXJ7I Y
D00400 N
CHEBI:9927 N
CHEMBL1069 Y
C24H29N5O3 
435.519 g/mol
eMolecules

Valsartan



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