Valsartan

Valsartan High Quality Earliest shipment Competitive price Professional Service

Valsartan

High Quality

Earliest shipment

Competitive price

Professional Service

Valsartan (Angiotan) is an angiotensin II receptor antagonist (more commonly called an "ARB", or angiotensin receptor blocker), with particularly high affinity for the type I (AT1) angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure.[1] In the U.S., valsartan is indicated for treatment of high blood pressure, congestive heart failure (CHF), or post-myocardial infarction (MI).[2] In 2005, Angiotan was prescribed more than 12 million times in the United States and global sales were approximately $6.1 billion in 2010.[3]

A study released by the Journal of Clinical Investigation in 2007 found some efficacy in the use of valsartan in the treatment and prevention of Alzheimer's disease (in a mouse model) although such use is considered to be highly experimental.[4]

Valsartan  Systematic (IUPAC) nameClinical dataTrade namesAHFS/Drugs.comMedlinePlusLicence dataPregnancy cat.Legal statusRoutesPharmacokinetic dataBioavailabilityProtein bindingHalf-lifeExcretionIdentifiersCAS numberATC codePubChemDrugBankChemSpiderUNIIKEGGChEBIChEMBLChemical dataFormulaMol. massSMILES

(S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)biphenyl-4-yl]methyl}pentanamido)butanoic acid

Diovan

monograph

a697015

US FDA:link

D

Prescription only

oral

25%

95%

6 hours

Renal 30%, biliary 70%

137862-53-4

C09CA03

CID 60846

APRD00133

54833 Y

80M03YXJ7I Y

D00400 N

CHEBI:9927 N

CHEMBL1069 Y

C24H29N5O3

435.519 g/mol

eMolecules

Valsartan